Evaluation of a non-invasive method of assessing opioid induced respiratory depression
نویسندگان
چکیده
منابع مشابه
Opioid-induced respiratory depression: reversal by non-opioid drugs
The human body is critically dependent on the ventilatory control system for adequate uptake of oxygen and removal of carbon dioxide (CO2). Potent opioid analgesics, through their actions on μ-opioid receptor (MOR) expressed on respiratory neurons in the brainstem, depress ventilation. Opioid-induced respiratory depression (OIRD) is potentially life threatening and the cause of substantial morb...
متن کاملPostoperative opioid-induced respiratory depression: a closed claims analysis.
BACKGROUND Postoperative opioid-induced respiratory depression (RD) is a significant cause of death and brain damage in the perioperative period. The authors examined anesthesia closed malpractice claims associated with RD to determine whether patterns of injuries could guide preventative strategies. METHODS From the Anesthesia Closed Claims Project database of 9,799 claims, three authors rev...
متن کاملIncidence, Reversal, and Prevention of Opioid-induced Respiratory Depression.
Opioid treatment of pain is generally safe with 0.5% or less events from respiratory depression. However, fatalities are regularly reported. The only treatment currently available to reverse opioid respiratory depression is by naloxone infusion. The efficacy of naloxone depends on its own pharmacological characteristics and on those (including receptor kinetics) of the opioid that needs reversa...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 2005
ISSN: 0003-2409
DOI: 10.1111/j.1365-2044.2005.04153.x